Shaoping Zhang, BS, MS, PhD

Associate Professor

Current Positions

Associate Professor of Iowa Institute for Oral Health
Associate Professor of Periodontics

Education

Doctor of Philosophy in Oral Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
Master in Oral and Maxillofacial Surgery, Sichuan University West China College of Stomatology (Former West China University of Medical Science), Chengdu, China
Master in Oral Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
Bachelor of Medicine (DDS equivalent) in Dentistry, West China University of Medical Science College of Stomatology, Chengdu, China

Licenses & Certifications

Periodontology Residency Training Certificate, University of North Carolina at Chapel Hill School of Dentistry, North Carolina
Dental Practice License, Public Health Bureau of Chaoyang District, China

Selected Awards & Honors

Teaching and Mentoring Award, American Association of Periodontology, Chicago, Illinois
Gold Medal Fellowship by ADA, American Dental Association (ADA) and Church & Dwight Co., Inc., Chicago, Illinois
2018 American Association for Dental Research (AADR)-Bloc Travel Grant, NIDCR, Alexandria, Virginia
Straumann SUPER Grant, Straumann USA, LLC, Andover, Massachusetts
American Academy of Periodontology (AAP) Foundation Educator Scholarship, AAP Foundation, chicago, Illinois
2014 Billy Pennel Research Competition-2nd place in the Clinical Research, Southern Academy of Periodontology (SAP), Wilmington, North Carolina
Ann and G.Randolph Babcock Fellowship for the 2012-2013 academic year, North Carolina Dental Foundation, Chapel Hill, North Carolina
North Carolina Local Section of the AADR-Derek T. Turner Student Research Award 1st Place in MS/MPH, NC Local AADR, Chapel Hill, North Carolina
American Academy of Periodontology (AAP)-Balint Orban Memorial Award in Clinical Science, American Academy of Periodontology (AAP), Chicago, Illinois
Freedland Advanced Dental Education Fellowship for the 2010-2011 academic year, North Carolina Dental Foundation, Chapel Hill, North Carolina

Professional Memberships

American Association of Immunologists (AAI)

Selected Publications

Zhuozhi Wang, Jue Hu, Jeffrey S Marschall, Ling Yang, Erliang Zeng, Shaoping Zhang, Hongli Sun. 2024.Antiaging Metabolite‐Based Polymeric Microparticles for Intracellular Drug Delivery and Bone Regeneration. Small Science. 4(10):2400201.PMID: 39386061.PMCID: PMC11460827.
Sun, L., Wang, L., Moore, B. B., Zhang, S., Xiao, P., Decker, A. M. & Wang, H. (2023). IL-17: Balancing Protective Immunity and Pathogenesis. Journal of Immunology Research 2023: 3360310. DOI: doi: 10.1155/2023/3360310.. PMID: 37600066. PMCID: PMC10439834.
Heath, B. R., Gong, W., Taner, H. F., Broses, L., Okuyama, K., Cheng, W., Jin, M., Fitzsimonds, Z. R., Manousidaki, A., Wu, Y., Zhang, S., Wen, H., Chinn, S. B., Xie, Y., Moon, J. J. & Lei, Y. L. (2023). Saturated fatty acids dampen the immunogenicity of cancer by suppressing STING. Cell Reports 42 (4) 112303. PMID: 36952341.
Zhang, J., Sun, L., Hikkaduwa Withanage, M., Sukirth, G. M., Williamson, M. A., Marchesan, J. T., Jiao, Y., Teles, F. R., Yu, N., Liu, Y., Wu, D., Moss, K. L., Mangalam, A. K., Zeng, E., Lei, Y. L. & Zhang, S. TRAF3IP2-IL-17 Axis Strengthens the Gingival Defense against Pathogens. Journal of Dental Research 102 (1) 103-115. DOI: 10.1177/00220345221123256. PMID: 36281065. PMCID: PMC9780753.
Zhang, J., Wang, A. X., Wu, Y. & Zhang, S. IL-1 receptor antagonist (IL-1RA) suppresses a hyper-IL-17 response-mediated bone loss in a murine experimental periodontitis. Archives of Oral Biology 144 10555. DOI: 10.1016/j.archoralbio.2022.105555. PMID: 36191445.
Hong, Q., Sun, H., Chen, M., Zhang, S. & Yu, Q. Plasma treatment effects on destruction and recovery of Porphyromonas gingivalis biofilms. PloS One 17 (9) e0274523. DOI: 10.1371/journal.pone.0274523 Free PMC article. PMID: 36103549. PMCID: PMC9473617.
Zhang, S., Phillips, K. H., Moss, K. L., Wu, D., Adam, H. S., Selvin, E., Demmer, R. T., Norby, F. L., Mustapha, I. Z. & Beck, J. D. Periodontitis and Risk of Diabetes in the Atherosclerosis Risk In Communities (ARIC) Study: A BMI-modified Association. The Journal of Clinical Endocrinology and Metabolism /Oxford 106 (9) e3346-e3358. DOI: 10.1210/clinem/dgab337. PMID: 33982107. PMCID: PMC8372648.
Zhang, S., Zhang, J., Sun, L. S., Hikkaduwa Withanage, M., Marchesan, J. & Zeng, E. (2021). TRAF3IP2-mediated IL-17 Pathway Enhances Gingival Defense in Periodontitis. Iowa City: IADR/AADR/CADR General Session (Virtual Experience).
Philips, K. H., Zhang, S., Moss, K., Ciarrocca, K. & Beck, J. D. (2021). Periodontal disease, undiagnosed diabetes, and body mass index: Implications for diabetes screening by dentists. Journal of the American Dental Association (1939) 152 (1) 25-35. DOI: 10.1016/j.adaj.2020.09.002. PMID: 33256949.
Wang, L., Tai-Hsien, W., Hu, X., Liu, J., Wu, D., Miguez, P. A., Wright, J. T., Zhang, S., Chi, J., Tseng, H. C. & Ko, C. Biomimetic polydopamine-laced hydroxyapatite collagen material orients osteoclast behavior to an anti-resorptive pattern without compromising osteoclasts’ coupling to osteoblasts. Biomaterials Science 9 (22) 7565-7574. DOI: 10.1039/d1bm01119g. PMID: 34664567.

Selected Grants & Contracts

Investigating the role of tumor necrosis factor-receptor associated factor 3 interacting protein 2 (TRAF3IP2), a critical adaptor in IL-17 pathway, in periodontal disease (R00); NIH-NIDCR; Zhang, Shaoping (Principal Investigator)
The Immunological and Osteological Roles of Interferon- β in Periodontal Disease; Institute of Iowa Oral Health Research, University of Iowa; Cao, Huojun (Co-Investigator), Zhang, Shaoping (Principal Investigator)
Identifying signature inflammatory mediators in gingival crevicular fluid in periodontal profile class-Stages; Colgate; Zeng, Erliang (Statistician), Zhang, Shaoping (Principal Investigator)
Investigating the role of tumor necrosis factor-receptor associated factor 3 interacting protein 2 (TRAF3IP2), a critical adaptor in IL-17 pathway, in periodontal disease (K99); NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH; Zhang, Shaoping (Principal Investigator)