Core Research Area

The University of Iowa College of Dentistry is a worldwide leader in studies of microbiology and the microbiome and their effects on caries progression, periodontal disease and on oral cancer.

The interactions between the host and its commensal oral microflora are complex yet profoundly affect the balance between health and disease.  College of Dentistry researchers are investigating this balance from a variety of perspectives -- microbial activity, inflammation, immunity, cell biology -- in an effort to understand how to maintain a healthy mouth or to restore health if disease occurs. 

Updates

Emily Lanzel working with equipment

UI Oral Cancer Researcher Receives Grant to Improve Machine Learning for Cancer Evaluation

Thursday, December 9, 2021
Emily Lanzel received a grant in collaboration with the University of Chicago to use digital pathology slides to improve machine learning algorithms for use as a tool to evaluate the risk of cancer.
Cristina Vidal working in her lab

NIH Awards Cristina Vidal $700K+ Grant

Friday, July 2, 2021
The National Institutes of Health (NIH) and the National Institute of Dental and Craniofacial Research (NIDCR) awarded Cristina Vidal, assistant professor in the Department of Operative Dentistry, a 5-year grant totaling over $700K for her research project studying the relationship between caries and the oral microbiome.
The utility company that serves the University of Iowa

College of Dentistry Awarded $600K+ in P3 Funds to Begin Developing a New Oral Cancer Center of Excellence

Friday, February 5, 2021
On Thursday, the University of Iowa announced that the first $7.5 million of the investment revenue generated from the public-private partnership (P3) for its utility system would include a $600K+ award for the College of Dentistry. With this support, an interdisciplinary team with over 40-people, including Iowa faculty from the Colleges of Dentistry, Medicine, Pharmacy, and Engineering, will develop the preliminary data and program structure to apply for and be competitive for an $11 million grant from the NCI/NIDCR to establish a P50 Specialized Program of Research Excellence in oral cancer. This specialized research program in oral cancer will be the first of its kind in the nation.